PHOTOCATALYTIC OXIDATION OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS
Konferenční objektOtevřený přístuppeer-reviewedpostprint Náhled není k dispozici
Datum publikování
2016
Vedoucí práce
Oponent
Název časopisu
Název svazku
Vydavatel
Česká společnost průmyslové chemie
Abstrakt
Pharmaceuticals diclofenac and naproxen belong to class of non-steroidal anti-inflammatory drugs (NSAIDs). These substances are very often found in outlets of WWTP or in surface waters, because among all classes of pharmaceuticals, they are frequently prescribed and purchased. These substances have by their nature a strong biological effect, so non-target organisms are affected. For example diclofenac causes cytological malformations of liver tissue within a concentration 28 μg/L (O. mykkis). Sensitive organisms to naproxen are crustaceans, where the EC50 for (C. dubia) is 330 μg/L, but degradation products of this drug are significantly more toxic. EC50 for degradation products of naproxen to C. dubia are less than 100 μg/L. Diclofenac and naproxen (500 μg/L) were from model water samples removed by heterogeneous photocatalysis in 4L batch reactor. After irradiation of the catalyst, the system produces •OH radicals, which causes destruction of the organic substance. As the catalyst used was 0.5 g/L titanium dioxide (TiO2, Precheza a.s.). As a source of UV radiation was used UV LED diode Luminus, with peak wavelength at 365 nm. At the same time the effect of hydrogen peroxide (H2O2) or effect of pH was determined. Samples were preconcentrated by solid phase extraction (SPE) and analyzed by high performance liquid chromatography (HPLC). At the same time characteristics and capability of pharmaceutical removal from inlet of WWTP were discussed.
Rozsah stran
p. 440-444
ISSN
2336-811X
Trvalý odkaz na tento záznam
Projekt
SGS_2016_002/Vývojové a aplikační metody a postupy environmentálního inženýrství a hodnotového managementu
Zdrojový dokument
Proceedings of the 4th International Conference on Chemical Technology
Vydavatelská verze
http://www.icct.cz/getattachment/PREDCHOZI-KONFERENCE/2016/Proceedings_ICCT2016.pdf.aspx
Přístup k e-verzi
open access
Název akce
4th International Conference on Chemical Technology ICCT 2016 (25.04.2016 - 27.04.2016)
ISBN
978-80-86238-94-4
Studijní obor
Studijní program
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Umístění tištěné verze
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Klíčová slova
diclofenac, naproxen, anti-inflammatory drugs, photocatalytic oxidation, diclofenac, naproxen, protizánětlivé léky, fotokatalytická oxidace