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PHOTOCATALYTIC OXIDATION OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS

Konferenční objektOtevřený přístuppeer-reviewedpostprint
Náhled není k dispozici

Datum publikování

2016

Vedoucí práce

Oponent

Název časopisu

Název svazku

Vydavatel

Česká společnost průmyslové chemie

Abstrakt

Pharmaceuticals diclofenac and naproxen belong to class of non-steroidal anti-inflammatory drugs (NSAIDs). These substances are very often found in outlets of WWTP or in surface waters, because among all classes of pharmaceuticals, they are frequently prescribed and purchased. These substances have by their nature a strong biological effect, so non-target organisms are affected. For example diclofenac causes cytological malformations of liver tissue within a concentration 28 μg/L (O. mykkis). Sensitive organisms to naproxen are crustaceans, where the EC50 for (C. dubia) is 330 μg/L, but degradation products of this drug are significantly more toxic. EC50 for degradation products of naproxen to C. dubia are less than 100 μg/L. Diclofenac and naproxen (500 μg/L) were from model water samples removed by heterogeneous photocatalysis in 4L batch reactor. After irradiation of the catalyst, the system produces •OH radicals, which causes destruction of the organic substance. As the catalyst used was 0.5 g/L titanium dioxide (TiO2, Precheza a.s.). As a source of UV radiation was used UV LED diode Luminus, with peak wavelength at 365 nm. At the same time the effect of hydrogen peroxide (H2O2) or effect of pH was determined. Samples were preconcentrated by solid phase extraction (SPE) and analyzed by high performance liquid chromatography (HPLC). At the same time characteristics and capability of pharmaceutical removal from inlet of WWTP were discussed.

Rozsah stran

p. 440-444

ISSN

2336-811X

Trvalý odkaz na tento záznam

Projekt

SGS_2016_002/Vývojové a aplikační metody a postupy environmentálního inženýrství a hodnotového managementu

Zdrojový dokument

Proceedings of the 4th International Conference on Chemical Technology

Vydavatelská verze

http://www.icct.cz/getattachment/PREDCHOZI-KONFERENCE/2016/Proceedings_ICCT2016.pdf.aspx

Přístup k e-verzi

open access

Název akce

4th International Conference on Chemical Technology ICCT 2016 (25.04.2016 - 27.04.2016)

ISBN

978-80-86238-94-4

Studijní obor

Studijní program

Signatura tištěné verze

Umístění tištěné verze

Přístup k tištěné verzi

Klíčová slova

diclofenac, naproxen, anti-inflammatory drugs, photocatalytic oxidation, diclofenac, naproxen, protizánětlivé léky, fotokatalytická oxidace

Endorsement

Review

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