Digitální knihovnaUPCE
 

Comparison of loading efficacy and capacity of ovalbumin modified chitosan-based nanoparticles and nanofibers

ČlánekOtevřený přístuppeer-reviewedpublished
Náhled

Datum publikování

2019

Vedoucí práce

Oponent

Název časopisu

Název svazku

Vydavatel

University of Pardubice

Abstrakt

In this paper, the suitability of nanomaterials for drug delivery systems was studied, including nanoparticle and nanofiber diameters measurement, when using the hydrodynamic light scattering, scanning electron microscopy, the optimization of protein concentration for adsorption, and of protein release assessment. The advantage of nanomaterials is their large surface area. The aim of a series of sorption experiments was to monitor the rate of sorption of ovalbumin (OVA) on three types of chitosan (CS)- based nanomaterial carriers – the nanoparticles of chitosan, the nanoparticles of chitosan-grafted-functionalized copolymer of polyacrylamide with polylactic acid (CS/PLA/PAA), and the electrospun nanofibers. In the nanomaterials, the loading efficacy and loading capacity were calculated and compared.

Rozsah stran

p. 53 - 64

ISSN

1211-5541

Trvalý odkaz na tento záznam

Projekt

Zdrojový dokument

Scientific papers of the University of Pardubice. Series A, Faculty of Chemical Technology. 25/2019

Vydavatelská verze

Přístup k e-verzi

open access

Název akce

ISBN

978-80-7560-243-5

Studijní obor

Studijní program

Signatura tištěné verze

Umístění tištěné verze

Přístup k tištěné verzi

Klíčová slova

protein adsorption, protein release, loading efficacy, loading capacity, nanomaterials

Endorsement

Review

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