Comparison of loading efficacy and capacity of ovalbumin modified chitosan-based nanoparticles and nanofibers

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dc.contributor.author Slováková, Marcela
dc.contributor.author Váňová, Veronika
dc.contributor.author di Martino, Antonio
dc.contributor.author Palarčík, Jiří
dc.contributor.author Munzarová, Marcela
dc.date.accessioned 2019-10-03T10:41:25Z
dc.date.available 2019-10-03T10:41:25Z
dc.date.issued 2019
dc.identifier.isbn 978-80-7560-243-5
dc.identifier.issn 1211-5541
dc.identifier.uri https://hdl.handle.net/10195/74266
dc.description.abstract In this paper, the suitability of nanomaterials for drug delivery systems was studied, including nanoparticle and nanofiber diameters measurement, when using the hydrodynamic light scattering, scanning electron microscopy, the optimization of protein concentration for adsorption, and of protein release assessment. The advantage of nanomaterials is their large surface area. The aim of a series of sorption experiments was to monitor the rate of sorption of ovalbumin (OVA) on three types of chitosan (CS)- based nanomaterial carriers – the nanoparticles of chitosan, the nanoparticles of chitosan-grafted-functionalized copolymer of polyacrylamide with polylactic acid (CS/PLA/PAA), and the electrospun nanofibers. In the nanomaterials, the loading efficacy and loading capacity were calculated and compared. en
dc.format p. 53 - 64
dc.language.iso en
dc.publisher University of Pardubice en
dc.relation.ispartof Scientific papers of the University of Pardubice. Series A, Faculty of Chemical Technology. 25/2019 en
dc.rights open access en
dc.subject protein adsorption en
dc.subject protein release en
dc.subject loading efficacy en
dc.subject loading capacity en
dc.subject nanomaterials en
dc.title Comparison of loading efficacy and capacity of ovalbumin modified chitosan-based nanoparticles and nanofibers en
dc.type Article en
dc.peerreviewed yes en
dc.publicationstatus published en


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