Flow injection tyrosinase amperometric biosensor with a single-layer graphene modified screen-printed electrode for determination of acetaminophen

Frangu, Arber; Sýs, Milan; Arbneshi, Tahir; Vytřas, Karel

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Flow injection tyrosinase amperometric biosensor with a single-layer graphene modified screen-printed electrode for determination of acetaminophen

Frangu, Arber; Sýs, Milan; Arbneshi, Tahir; Vytřas, Karel

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URI: https://hdl.handle.net/10195/72479

Datum publikování: 2018

Document type: ConferenceObject

xmlui.ArtifactBrowser.SimpleSearch.filter.source: XXXVIII. Moderní elektrochemické metody : sborník příspěvků

Publisher version: https://www.bestservis.eu/images/file/Sbornik_metody18_pdf/Sbornik_metody18.pdf

xmlui.ArtifactBrowser.SimpleSearch.filter.event XXXVIII. Moderní elektrochemické metody (21.05.2018 - 25.05.2018, Jetřichovice)

Abstract:

The aim of this study was to develop an amperometric biosensor utilizing mushroom (Agaricus bisporus) tyrosinase (EC 1.14.18.1) suitable for the selective determination of acetaminophen in human urine. The presented biological device was based on a commercial screen-printed carbon electrode covered with a thin graphene layer (transducer) with an enzyme (bioreceptor) immobilized with glutaraldehyde and Nafion®, and tested on spiked human urine samples.

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