Digitální knihovnaUPCE
 

GC/MS and FAB/MS analysis of lipid molecules for taxonomic classification of microorganisms

ČlánekOtevřený přístuppeer-reviewedpublished
Náhled

Datum publikování

2005

Vedoucí práce

Oponent

Název časopisu

Název svazku

Vydavatel

Univerzita Pardubice

Abstrakt

The goal of this project was to identify the presence of microorganisms in the environment by using their gas chromatography/mass spectral (GC/MS) characteristics as biomarkers. A combination of GC/MS results and pattern recognition statistical evaluation were used to provide a mathematical model with defined parameters for different microorganisms, which allows the organisms to be classified as bacterial, fungal or viral nature. Results from fast atom bombardment mass spectral (FAB/MS) analysis showed differences in the complex lipid profiles for most of the analyzed microorganisms. A general screening method that can provide early detection of microorganisms would permit initiation of most therapeutics. Various drugs are used to treat bacterial, fungal or viral diseases and, when treatment is started early, there is a dramatic reduction in mortality. A methodology for detection and classification of microorganisms is described in this paper.

Rozsah stran

p. 131-146

ISSN

1211-5541

Trvalý odkaz na tento záznam

Projekt

Zdrojový dokument

Scientific papers of the University of Pardubice. Series A, Faculty of Chemical technology. 10 (2004)

Vydavatelská verze

Přístup k e-verzi

open access

Název akce

ISBN

Studijní obor

Studijní program

Signatura tištěné verze

47333

Umístění tištěné verze

Univerzitní knihovna (studovna)

Přístup k tištěné verzi

Klíčová slova

plynová chromatografie, Hmotnostní spektrometrie, mikroorganismy, Klasifikace, Tuky

Endorsement

Review

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