Voltammetric method for determination of muscle relaxant dantrolene sodium using a boron-doped diamond electrode

Abstract

In this work, the electrochemical behavior of the dantrolene sodium muscle relaxant has been studied and the voltammetric method for its determination using a boron-doped diamond electrode (BDDE) proposed. Cyclic voltammetry and direct current voltammetry has been used for study of the dependences of DAN voltammetric signals on pH and scan rate. Differential pulse voltammetry and direct current voltammetry in combination with BDDE were applied to develop a sensitive method for the determination of the electroactive compound tested and various analytical and statistical parameters were calculated, e.g., the relative standard deviation of repeated measurements or limit of detection and limit of quantification.