Innovative configurations of electrochemical DNA biosensors (a review)

Abstract

In the field of electrochemical biosensing, transition metal complexes achieved a significant importance as hybridization indicators or electroactive markers of DNA. Their incorporation in electro-chemical DNA biosensors enables to offer a promising perspective in understanding of the biological activity of some chemical compounds. In this context, the development of innovative configurations of electrochemical DNA biosensors applied to life sciences during the last years were reviewed in the present article. In the first part, a brief introduction of nanomaterial based electrochemical DNA biosensors is given. In the second part, the complexes of transition metals with biological interest and their applications in electrochemical DNA biosensors are being described.