Electrochemical techniques as promising analytical tools in the DNA electrochemistry (a review)

Abstract

In the present article, the research and development of electrochemical techniques, namely voltammetric measurements, applied in the DNA electroanalysis during the past years have been reviewed (in five parts). In the first section, the applications of DNA electrochemistry in the detection of metals are being thoroughly described. The second part gives a critical view in the study of interaction between metals and DNA using electrochemical techniques. Furthermore, attention is paid to the metals and DNA damage detection using selected electrochemical techniques. The following part offers discussion on the detection of DNA sequences / oligonucleotides using metals and electrochemical techniques. Finally, in the last part, the interactions between the antitumor drugs and DNA when using electrochemical techniques are being concerned and critically evaluated.